In this western, the Three Mesquiteers must find a killer and his band after they murder an official from the State Agricultural Service who had come to investigate an outbreak of hoof and mouth disease. The killer is fearful that the official would quarantine his entire herd. Unfortunately for the foolish rancher, if the herd is not isolated, all of his cows and those of his neighbors will die anyway. The heroes are assisted by Buck the clever Great Dane.
When Bill Hinchley is wrongfully imprisoned his wife, Mary, becomes a schoolteacher out of necessity concealing from the school trustees that she is the wife of a convict. Sneaky Pete, Bill's cellmate, steals a letter from Mary to Bill, and, his term expired, follows Mary and extorts her, by threatening to cause her to lose her job by revealing her secret. Attempting to escape Bill gives up his chance at freedom to rescue the warden's children - and is later pardoned, coming home to wreak vengeance on Sneaky Pete, and justify Mary's faith in him.
Olive's ranch needs a helper, and the boys just happen to be passing by. Bluto's convinced he's better, but Popeye wins at all of Olive's tests: riding a bronco and branding. As Popeye wins the job, Bluto starts a stampede and a fire simultaneously. With some spinach help, Popeye gets Bluto out of the way, douses the fire, and saves Olive from the stampede.
Broncho Billy, in a quarrel with Faro Dan, a card sharp, shoots him and flees. Pursued, he hides in the wagon of a man whom he meets on the prairie. The posse is misled by Broncho Billy's friend and the fugitive escapes. Several years later Broncho is made sheriff of an adjoining county.
In a time when poor mexicans, contemptuously called indians, were treated as slaves by the rich. Things were unfair, unbalanced. Django, a mexican indian, runs for his life trying to escape his abusive patrón... but he fails. After a beating that renders him unconscious, he awakens to meet Dr. Shultz, a bounty hunter that likes to keep thing in balance. Dr. Shultz has a lot to teach Django, about bounty hunters and the way of the gun, so Django can live.
Mustang Pete receives a letter from his daughter, Sophie, who is away at boarding school, asking permission to bring some girls home with her to spend their vacation. Mustang flatly refuses. That afternoon he and Slippery Slim have a fight over a checker game, and to get "square" Slim advertises the fact that he will pay his ranch hands double the salary that Mustang will pay. As a result Slim gets all of Mustang's helpers. Mustang then writes to Sophie and tells her to bring home the girls if she cares to. The girls arrive the following day and Mustang has an abundance of help, all of Slim's helpers deserting him.
In the 1880's a ruthess gang of outlaws terroized the Southwest. These renegades were led by the notorious Bloody Jack Ryker and his top gun, Johnny Vermillion. Three men stood in their way. Stormy Lane and his two sidekicks, Cimarron Simmons and Texas Clapsaddle with the help of young Billy Wood pursue this band of cutthroats through the badlands of Texas.
Tom Drury, a cowboy whose quick thinking stops a notorious outlaw, "The Hawk," from further misdeeds. The villain, as it turns out, is none other than Henry Suggs (James Mason), heretofore considered a pillar of the community.....
Chad Rainey, a young boy from Ohio looses his mother to Cholera. On his way west on a wagon train he elopes into the wilderness where he meets and fall in love with an Indian girl.
Millionaire Larry Prentiss inherits a ranch. He decides to visit his new property incognito and gets a job as a ranch-hand. He falls in love with the ranch foreman's daughter and complications ensue.
A Mexican bandit and his gang are offered a pardon and a cash reward if he will cross the border into America and bring back a gang of murderous gold thieves who robbed the local church and killed the priest and the Head Federales' wife and children.
Tom Fleming, a Western bandit, and his pal, Morgan, hold up the stage. Fleming dispatches Morgan to town to inform him when the stage leaves. Fleming now receives a letter from his wife back east, in which she tells him she and their little girl pray every night that he will always remain an honest, faithful husband and father.
An 'out of place' American cowboy struggles to find his place in a small town in North-Western England. When his prize animal goes missing, he seizes the chance for redemption and goes on the hunt to get it back.
Tom is given the position of Cowboy on Sid Jordan's ranch. Vicky, Sid's daughter, is annoyed by Buck, the ranch foreman, who is discharged and Tom is given the position.
Ed King travels east to sell Pop Blake's cattle. While there Buck, another of Blake's hands, plans to rob Ed by using a local girl Ming Toy as a decoy. Ming Toy gets the money and returning empty handed, and before the other hands arrive, Ed is surprised to find Ming Toy return with the men.